Repetitivní transkraniální magnetická stimulace v léčbě deprese

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Title in English	Repetitive transcranial magnetic stimulation in the treatment of depression
Authors	USTOHAL Libor
Year of publication	2010
Type	Article in Periodical
Magazine / Source	Psychiatrie pro praxi
MU Faculty or unit	Faculty of Medicine
Citation
Field	Psychiatry, sexuology
Keywords	depression; principle of rTMS contraindications of rTMS; antidepressive effect of rTMS, efficacy of rTMS
Description	This article concerns with the use of repetitive transcranial magnetic stimulation (rTMS) in the treatment of depression. Its principal is to influence the brain using variable magnetic field. Tjhis method is safe and well tolerated with the minimum of side-effects. We have most experiences in psychiatry just in the treatment of depression. It is documented that rTMS influences cortical excitability and metabolic activity of neuronal cells. Is hat been conducted a lot of studies of its efficacy ih the treatment of depression, which can be divided into three generations. their outcomes were summarized in several metaanalyses. Last metaanalyses confirm that rTMS is a promising therapeutic method, although a lot of questions concerning especially with an exact mechanism of its action, optimal stimulation parameters and a selection of ptimal patients, remain unanswered.
Related projects:	The internal organisation and neurobiological mechanisms of functional CNS systems under normal and pathological conditions. Funkční mozkové koreláty související s léčbou negativních příznaků schizofrenie repetitivní transkraniální magnetickoustimulací