Comparison of baroreflex sensitivity determined by cross-spectral analysis at respiratory and 0.1 Hz frequencies
| Authors | |
|---|---|
| Year of publication | 2010 |
| Type | Article in Periodical |
| Magazine / Source | Physiological Research |
| MU Faculty or unit | |
| Citation | |
| Field | Physiology |
| Keywords | Baroreflex sensitivity; controlled breathing; spectral analysis; hypertension |
| Description | The aim of the present study was to evaluate the role of breathing in the spectral method of BRS determination with respect to age and hypertension. Blood pressure was recorded by Finapres (5 minutes, controlled breathing at 0.33 Hz) in 118 healthy young subjects (YS: mean age 21.0 years), 26 hypertensive patients (HT: mean age 48.6 years) with 26 age-matched controls (CHT: mean age 46.3 years). A comparison of BRS0.1Hz and BRS0.33Hz was made. Statistically significant correlations were found between BRS0.1Hz and BRS0.33Hz in all groups. The ratios of BRS0.1Hz to BRS0.33Hz were significantly lower than 1 (p, 0.01) in all groups. Thus, BRS evaluated at the breathing rate overestimates the real baroreflex sensitivity. This is more pronounced at low values of BRS. |
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