Applications of Capillary Electrophoresis using gold nanoparticles
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| Year of publication | 2008 |
| Type | Conference abstract |
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| Description | Ńanoparticles (NP) are measured in nanometers (nm) and they should have with at least one dimension < 200 nm. Nanoparticles are also solid colloidal particles ranging in size from 10 to 1000 nm. Unique size-dependent properties of NP make them more significant as they show unusual physical, chemical and biological properties. Gold nanoparticles (GNP) have been known since ancient times. For example, Romans and Greeks used them to colour glass, alchemists prepared a potion, called “Aurum potable”. Faraday in 1857 was perhaps the first one to understand that the colour of gold solutions was due to small size of gold particles. Nanoparticles are having a high impact on nanotechnology and nanomedicine [1]. GNP can be formed by laser ablation of gold but usually they are obtained by reducing Au(III) salts using suitable reducing agents. GNP represent tiny particles from a few gold atoms up to hundreds/thousands of atoms. As they are quite reactive the GNP particles are usually covered with a suitable layer of organic, e.g. with thiols (FIGURE 1). Gold clusters show various size, shape and colour (FIGURE 2). Colloidal gold nanoparticles have been separated according to the size and structure [2]. Because of the increasing importance of GNP in medicine and the use of GNP as markers for biomolecules, we have studied in this work electrophoretic behaviour of GNP formed in aqueous solution from various precursors while GNP were not stabilized by any organics. |
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