Memantine inhibits CYP2D2 metabolic activity in rats, in vitro and in vivo studies.

Zendulka,  Ondřej; Juřica,  Jan; Zendulková Zahradníková,  Lucia; Šulcová,  Alexandra

Memantine inhibits CYP2D2 metabolic activity in rats, in vitro and in vivo studies.

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Authors	ZENDULKA Ondřej JUŘICA Jan ZAHRADNÍKOVÁ Lucia ŠULCOVÁ Alexandra
Year of publication	2010
Type	Conference abstract
MU Faculty or unit	Faculty of Medicine
Citation
Description	Memantine is an inhibitor of CYP2D2 in rats in both experimental models used and moreover the inhibition of fluoxetine was modulated by memantine administration.
Related projects:	The internal organisation and neurobiological mechanisms of functional CNS systems under normal and pathological conditions.