Systems biology at work

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Authors	MARTINS DOS SANTOS V.A.P. DAMBORSKÝ Jiří
Year of publication	2010
Type	Article in Periodical
Magazine / Source	Current Opinion in Biotechnology
MU Faculty or unit	Faculty of Science
Citation
Web	http://www.sciencedirect.com
Field	Biochemistry
Keywords	Editorial overview; systems biology;engineering
Description	A core paradigm in systems biology is that biological systems are essentially built of highly coordinated sets of interacting networks across different scales [2]. Accordingly, biological behaviour can be thus described in terms of network properties and of their responses to internal and external perturbations, those being genetic, for example mutations, evolutionary rearrangement, or external, such as through the addition of chemicals or environmental changes.
Related projects:	Proteins in metabolism and interaction of organisms with the environment Interactions among the chemicals, environment and biological systems and their consequences on the global, regional and local scales (INCHEMBIOL) Center of Biocatalysis and Biotransformation Specific ion effects for proteins in solutions and related biologically relevant systems Evolution of substrate specificity in enzymes acting on xenobiotic compounds Analysis and Visualization of Protein Structures Centrum pro výzkum toxických látek v prostředí