Současný pohled na indikace podání kombinace inhibitorů ACE a sartanů

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Title in English Current perspective on indications for administering the combination of ACEI and sartans
Authors

VÍTOVEC Jiří ŠPINAR Jindřich

Year of publication 2010
Type Article in Periodical
Magazine / Source Interní medicína pro praxi
MU Faculty or unit

Faculty of Medicine

Citation
Field Other specializations of internal medicine
Keywords angiotenzin-converting enzyme inhibitors; angiotenzin II type 1 receptor blockers (sartans); hypertension; heart failure; myocardial infarction; coronary artery disease
Description The article deals with the pathophysiological basis for the combination of angiotenzin-converting enzyme (ACE) inhibitors and angiotenzin II type 1 receptor blockers (sartans) in the treatment of hypertension, heart failure and conditions after myocardial infarction and in the secondary prevention of coronary artery disease. The risks of combining these substances are discussed, particularly in terms of recent critical literature reviews of this combination, and a very careful consideration of the indications for coadministration of ACE inhibitors and sartans is emphasised.
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