Analýza "default mode" sítě u zdravých dobrovolníků
| Title in English | "Default Mode" Network Analysis in Healthy Volunteers |
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| Authors | |
| Year of publication | 2010 |
| Type | Article in Periodical |
| Magazine / Source | Ceska a slovenska neurologie a neurochirurgie |
| MU Faculty or unit | |
| Citation | |
| Field | Neurology, neurosurgery, neurosciences |
| Keywords | default mode network; functional magnetic resonance; cognitive task; deactivations; resting state |
| Description | The default mode network (DMN) is an organized network of brain structures involved in brain activity that may be observed in the resting state. In the course of the performance of an experimental cognitive task during functional MRI examination (fMR), these regions manifest as "deactivations". The main areas involved in this network are the ventromedial prefrontal cortex/anterior cingulate cortex, posterior cingulate cortex/precuneus and angular gyrus/inferior parietal cortex. In a group of 10 healthy volunteers, to detect DMN we used deactivations related to a visual spatial memory task; seed functional connectivity from the specific region of interest (cluster posterior cingulate cortex/precuneus); and independent component analysis (ICA). The ICA approach revealed a higher correlation rate with the results from functional connectivity compared to deactivation mapping. We found correlation between MRI signal in the cluster posterior cingulate cortex/precuneus and cognitive performance. |
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