Metabolomika – základní pojmy, strategie a metodologie

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Title in English	Metabolomics – basic concepts, strategies and methodologies.
Authors	MUSILOVÁ Jindra GLATZ Zdeněk
Year of publication	2011
Type	Article in Periodical
Magazine / Source	Chemické listy
MU Faculty or unit	Faculty of Science
Citation
Field	Biochemistry
Keywords	metabolomics; metabolome; metabolism; NMR; MS; GS; HPLC; CE
Description	This review defines the term “metabolomics” and clarifies its history and significance. The different strategies of metabolomics research are described together with their main application fields. Then the review focuses on the ways of sample preparations and on the analytical methodologies that are most frequently used for metabolomic studies - NMR, MS, GC/MS, HPLC/MS and CE/MS. Practical importance of metabolomics and its role in the systems biology are mentioned as well.
Related projects:	Proteins in metabolism and interaction of organisms with the environment Integrované bioanalytické technologie pro mikroanalýzy a diagnostiku s využitím LIF a hmotnostní spektrometrie Capillary electrophoresis as a member of the metabolomic analytical toolbox