Methamphetamine does not influence the metabolic activity of CYP 1A2, 2C6 and 2D2 isoenzymes in the animal study

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Authors	ZENDULKA Ondřej JUŘICA Jan SABOVÁ Michaela ŠULCOVÁ Alexandra
Year of publication	2010
Type	Article in Periodical
Magazine / Source	Activitas Nervosa Superior Rediviva
MU Faculty or unit	Faculty of Medicine
Citation
Web	http://www.rediviva.sav.sk/52i4/269.pdf
Field	Pharmacology and pharmaceutical chemistry
Keywords	methamphetamine; cytochrome P450; isolated perfused rat liver
Description	Graduating doses (2,5-10 mg kg day)of methamphetamine administered for 10 days did not significantly influenced the metabolic activity of hepatic CYP450 1A2, 2C6 and 2D2.
Related projects:	The internal organisation and neurobiological mechanisms of functional CNS systems under normal and pathological conditions.