Matrix metalloproteinase 8 (MMP8) gene polymorphisms in chronic periodontitis

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Authors	IZAKOVIČOVÁ HOLLÁ Lydie HRDLIČKOVÁ Barbara VOKURKA Jan FASSMANN Antonín
Year of publication	2012
Type	Article in Periodical
Magazine / Source	Arch Oral Biol
MU Faculty or unit	Faculty of Medicine
Citation
Doi	http://dx.doi.org/10.1016/j.archoralbio.2011.08.018
Field	ORL, ophthalmology, stomatology
Keywords	gene polymorphism; MMPs; periodontitis; periodontal pathogen
Description	Previous studies have suggested that some functional polymorphisms in the matrix metalloproteinase (MMPs) genes are associated with the risk of periodontal disease. However, to date no study has investigated MMP8 gene variants in relation to chronic periodontitis (CP). The aim of this study was to analyze polymorphisms in the MMP8 gene and their associations with microbial composition and clinical manifestation of CP.
Related projects:	Dental research centre Mikrobiologické a genetické determinanty rozvoje a progrese parodontitidy u diabetiků 1. a 2. typu a jejich reciproční vztah ke kompenzaci diabetu