New pH dependent lectin from bioluminescent bacterium  Photorhabdus luminescens

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Authors	ROZUMOVÁ Petra WIMMEROVÁ Michaela
Year of publication	2011
Type	Conference abstract
MU Faculty or unit	Faculty of Science
Citation
Description	Photorhabdus luminescens is a gram-negative symbiotic bacterium that lives in the gut of entomopathogenic nematodes. The protein PLU from P. luminescens has a strong sequence homology with the recently characterized lectin BC2L-C-nt from the human opportunistic pathogen Burkholderia cenocepacia. BC2L-C-nt is an attractive protein, since it has unique beta sandwich trimeric structure and is the first lectin with TNF-fold. The contribution is focused on characterization of lectin PLU from P. luminescens.
Related projects:	Proteins in metabolism and interaction of organisms with the environment Design of Carbohydrates and Glycomimetics as Antibacterial and Antiviral Drugs Molekulární a strukturní biologie vybraných cytostatik. Od mechanických studií k chemoterapii rakoviny