Akutní léčba deprese u bipolární afektivní poruchy
| Title in English | Acute treatment of bipolar depression |
|---|---|
| Authors | |
| Year of publication | 2011 |
| Type | Article in Periodical |
| Magazine / Source | Psychiatrie pro praxi |
| MU Faculty or unit | |
| Citation | |
| Field | Psychiatry, sexuology |
| Keywords | bipolar depression; guideline; lamotrigine; treatment; lithium; olanzapine; quetiapine; review; valproate |
| Description | In the last years new data have been published on the acute treatment of depression of bipolar affective disorder. They have been subsequently involved in the guidelines and treatment algorithms of bipolar affective disorder. Unfortunately, they often led to conflicting conclusions and recommendations due to limitations of the available literature. As a general approach during depressive episodes in bipolar disorder most guidelines suggest lithium, lamotrigine or quetiapine monotherapy as first-line choice. If psychotic features are present, to add an antipsychotic such as olanzapine, quetiapine or risperidone. The use of an antidepressant with caution, always in combination with quetiapine, lamotrigine or mood stabilizer. Although guidelines cannot substitute professional knowledge and clinical judgement, they might be a useful tool for clinicians in order to orientate their practice towards evidence base. |
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