FREQUENCY OF THE SPECTRAL PEAK IN THE RANGE OF FREQUENCIES BETWEEN 60 AND 120 mHz IN CROSSSPECTRA OF BLOOD PRESSURE AND HEART RATE FLUCTUATION IN YOUNG DIABETICS
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| Year of publication | 2010 |
| Type | Conference abstract |
| MU Faculty or unit | |
| Citation | |
| Description | The relatively well-preserved baroreflex sensitivity (BRS) in young diabetics is accompanied by an increased time delay within the baroreflex loop and a decrease in the synchronisation level between blood pressure and heart rate fluctuations. The aim of the present study was the determination of the frequency of the spectral peak (f) in crossspectra of systolic blood pressure and heart rate fluctuations (frequency range between 60 and 120 mHz) and BRS by the spectral method in young diabetics and matched healthy controls. We investigated 14 type- 1 diabetics (age 20-25 years, diabetes duration 10-15 years) and 14 agematched controls. Blood pressure and heart rate were recorded beat-tobeat by Finapres for 40 minutes. BRS was determined by the spectral method, f was measured in the cross-spectra of systolic blood pressure and heart rate fluctuations. Mean BRS was 14.58 ms/mmHg in controls and 10.31 ms/mmHg in diabetics. The difference was statistically insignificant (p=0.06). Mean f was 93.70 mHz in controls and 88.79 mHz in diabetics; the difference was significant. It is concluded that the frequency of the spectral peak in the cross-spectra of systolic blood pressure and heart rate fluctuations in the range between 60 and 120 mHz is decreased in young diabetics and provides a diagnostic tool for the detection of autonomic nervous system impairment in these patients. |
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