AIFM2 (apoptosis-inducing factor, mitochondrion-associated, 2)

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Authors	VAŘECHA Miroslav
Year of publication	2010
Type	Article in Periodical
Magazine / Source	Atlas of Genetics and Cytogenetics in Oncology and Haematology
MU Faculty or unit	Faculty of Informatics
Citation
Web	http://documents.irevues.inist.fr/handle/2042/44747
Doi	http://dx.doi.org/10.4267/2042/44747
Field	Genetics and molecular biology
Keywords	AIFM2;AMID;PRG3;mitochondria
Attached files	06-2009-AIFM2ID41842ch10q22.pdf
Description	AIFM2 is oxidoreductase of 373 AA lenght. It is predicted to take part in caspase-independent apoptosis similarly to homologous AIFM1 (AIF, PDCD8). AIFM2 is p53-responsive gene and production of AIFM2 was found to be suppressed in many human cancers.
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