Haplotype analysis of the IL-10 promoter polymorphisms and microbial composition in patients with chronic and aggressive periodontitis

Izakovičová Hollá,  Lydie; Bořilová Linhartová,  Petra; Bučková,  Dana; Vokurka,  Jan; Fassmann,  Antonín

Haplotype analysis of the IL-10 promoter polymorphisms and microbial composition in patients with chronic and aggressive periodontitis

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Authors	IZAKOVIČOVÁ HOLLÁ Lydie LINHARTOVÁ Petra BUČKOVÁ Dana VOKURKA Jan FASSMANN Antonín
Year of publication	2012
Type	Conference abstract
MU Faculty or unit	Faculty of Medicine
Citation
Description	Interleukin-10 (IL-10) is a key regulatory cytokine that has a significant effect on both the innate and adaptive immune response. The aim of this study was to analyze polymorphisms in the IL-10 gene and their associations with microbial composition and clinical manifestation of chronic (CP) or aggressive (AgP) periodontitis.
Related projects:	Mikrobiologické a genetické determinanty rozvoje a progrese parodontitidy u diabetiků 1. a 2. typu a jejich reciproční vztah ke kompenzaci diabetu