Současné možnosti výběru spermie v asistované reprodukci
| Title in English | Advanced methods of sperm selection in assisted reproduction |
|---|---|
| Authors | |
| Year of publication | 2012 |
| Type | Article in Periodical |
| Magazine / Source | Moderní gynekologie a porodnictví |
| MU Faculty or unit | |
| Citation | |
| Field | Gynaecology and obstetrics |
| Keywords | assisted reproductive techniques; hyaluronic acid binding; magnetic cell sorting; sperm selection |
| Attached files | |
| Description | Current routine semen preparation techniques do not target all intrinsic sperm characteristics that may impact the fertilization potential. Several methods have been recently developed and applied to sperm selection. Current advanced sperm selection methods are based on surface charge (electrophoresis and zeta potential), apoptosis (magnetic cell sorting and glass wool), membrane maturity (hyaluronic acid binding) and ultramorphology (high magnification). Selection of high-quality sperm including improvements in DNA integrity could improve fertilization and pregnancy rates. |
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