Nucleosomal TATA-switch: Competing orientations of TATA on the nucleosome
Autoři | |
---|---|
Rok publikování | 2013 |
Druh | Článek v odborném periodiku |
Časopis / Zdroj | Gene |
Fakulta / Pracoviště MU | |
Citace | |
Doi | http://dx.doi.org/10.1016/j.gene.2013.06.004 |
Obor | Genetika a molekulární biologie |
Klíčová slova | TATA box; Eukaryotic promoter; Nucleosome mapping; Rotational positioning; Chromatin and transcription |
Popis | Transcription is known to be affected by the rotational setting of the transcription response elements within nucleosomes.Our results show that the nucleosome DNA sequence harboring the TATA box encodes alternative rotational positions for the same piece of DNA. This may serve for switching the gene activity on and off. |
Související projekty: |