Circulating MiR-130a monitoring in multiple myeloma patients and patients with extramedullary disease

Varování

Publikace nespadá pod Ústav výpočetní techniky, ale pod Lékařskou fakultu. Oficiální stránka publikace je na webu muni.cz.

Autoři	BEŠŠE Lenka SEDLAŘÍKOVÁ Lenka KRYUKOV Fedor RADOVÁ Lenka NEKVINDOVA Jana NĚMEC Pavel DRANDI Daniela CALTAGIRONE Simona OMEDE Paola KREJČÍ Marta ADAM Zdeněk POUR Luděk ŠEVČÍKOVÁ Sabina PALUMBO Antonio BOCCADORO Mario HÁJEK Roman
Rok publikování	2014
Druh	Další prezentace na konferencích
Fakulta / Pracoviště MU	Lékařská fakulta
Citace
Přiložené soubory	EL_1228925.pdf
Popis	MicroRNAs (miRNAs) are a class of short, non-coding, single stranded RNAs regulating a broad spectrum of processes. Circulating miRNAs are an important emerging biomarker in cancer as well as a possible non-invasive diagnostic solution for a wide range of clinical disorders due to their high stability and association with disease state, although their source still remains uncertain. In multiple myeloma (MM), a plasma cell malignancy, circulating miRNAs have been reported to have a diagnostic and prognostic potential. It is therefore plausible to assume that they are involved in pathogenesis of this disease and thus could be used as diagnostic tool not only for MM, itsextramedullary (EM) form but also for monitoring the clinical course of the disease. Therefore, in this study, we aimed to identify such miRNAs.
Související projekty:	Molekulární charakteristika centrozomálních abnormalit a jejich prognostický význam pro pacienty s mnohočetným myelomem