GA4GH: International policies and standards for data sharing across genomic research and healthcare
| Autoři |
REHM Heidi L PAGE Angela J H SMITH Lindsay ADAMS Jeremy B ALTEROVITZ Gil BABB Lawrence J BARKLEY Maxmillian P BAUDIS Michael BEAUVAIS Michael J S BECK Tim BECKMANN Jacques S BELTRAN Sergi BERNICK David BERNIER Alexander BONFIELD James K BOUGHTWOOD Tiffany F BOURQUE Guillaume BOWERS Sarion R BROOKES Anthony J BRUDNO Michael BRUSH Matthew H BUJOLD David BURDETT Tony BUSKE Orion J CABILI Moran N CAMERON Daniel L CARROLL Robert J CASAS-SILVA Esmeralda CHAKRAVARTY Debyani CHAUDHARI Bimal P CHEN Shu Hui CHERRY J Michael CHUNG Justina CLINE Melissa CLISSOLD Hayley L COOK-DEEGAN Robert M COURTOT Melanie CUNNINGHAM Fiona CUPAK Miro DAVIES Robert M DENISKO Danielle DOERR Megan J DOLMAN Lena I DOVE Edward S DURSI L Jonathan DYKE Stephanie O M EDDY James A EILBECK Karen ELLROTT Kyle P FAIRLEY Susan FAKHRO Khalid A FIRTH Helen V FITZSIMONS Michael S FIUME Marc FLICEK Paul FORE Ian M FREEBERG Mallory A FREIMUTH Robert R FROMONT Lauren A FUERTH Jonathan GAFF Clara L GAN Weiniu GHANAIM Elena M GLAZER David GREEN Robert C GRIFFITH Malachi GRIFFITH Obi L GROSSMAN Robert L GROZA Tudor AUVIL Jaime M Guidry GUIGO Roderic GUPTA Dipayan HAENDEL Melissa A HAMOSH Ada HANSEN David P HART Reece K HARTLEY Dean Mitchell HAUSSLER David HENDRICKS-STURRUP Rachele M HO Calvin W L HOBB Ashley E HOFFMAN Michael M HOFMANN Oliver M HOLUB Petr HSU Jacob Shujui HUBAUX Jean-Pierre HUNT Sarah E HUSAMI Ammar JACOBSEN Julius O JAMUAR Saumya S JANES Elizabeth L JEANSON Francis JENE Aina JOHNS Amber L JOLY Yann JONES Steven J M KANITZ Alexander KATO Kazuto KEANE Thomas M KEKESI-LAFRANCE Kristina KELLEHER Jerome KERRY Giselle KHOR Seik-Soon KNOPPERS Bartha M KONOPKO Melissa A KOSAKI Kenjiro KUBA Martin LAWSON Jonathan LEINONEN Rasko LI Stephanie LIN Michael F LINDEN Mikael LIU Xianglin LIYANAGE Isuru Udara LOPEZ Javier LUCASSEN Anneke M LUKOWSKI Michael MANN Alice L MARSHALL John MATTIONI Michele METKE-JIMENEZ Alejandro MIDDLETON Anna MILNE Richard J MOLNAR-GABOR Fruzsina MULDER Nicola MUNOZ-TORRES Monica C NAG Rishi NAKAGAWA Hidewaki NASIR Jamal NAVARRO Arcadi NELSON Tristan H NIEWIELSKA Ania NISSELLE Amy NIU Jeffrey NYRONEN Tommi H CONNOR Brian D OESTERLE Sabine OGISHIMA Soichi WANG Vivian Ota PAGLIONE Laura A D PALUMBO Emilio PARKINSON Helen E PHILIPPAKIS Anthony A PIZARRO Angel D PRLIC Andreas RAMBLA Jordi RENDON Augusto RIDER Renee A ROBINSON Peter N RODARMER Kurt W RODRIGUEZ Laura Lyman RUBIN Alan F RUEDA Manuel RUSHTON Gregory A RYAN Rosalyn S SAUNDERS Gary I SCHUILENBURG Helen SCHWEDE Torsten SCOLLEN Serena SENF Alexander SHEFFIELD Nathan C SKANTHARAJAH Neerjah SMITH Albert V SOFIA Heidi J SPALDING Dylan SPURDLE Amanda B STARK Zornitza STEIN Lincoln D SUEMATSU Makoto TAN Patrick TEDDS Jonathan A THOMSON Alastair A THOROGOOD Adrian TICKLE Timothy L TOKUNAGA Katsushi TOMROOS Juha TORRENTS David UPCHURCH Sean VALENCIA Alfonso GUIMERA Roman Valls VAMATHEVAN Jessica VARMA Susheel VEARS Danya F VINER Coby VOISIN Craig WAGNER Alex H WALLACE Susan E WALSH Brian P WILLIAMS Marc S WINKLER Eva C WOLD Barbara J WOOD Grant M WOOLLEY J Patrick YAMASAKI Chisato YATES Andrew D YUNG Christina K ZASS Lyndon J ZAYTSEVA Ksenia ZHANG Junjun GOODHAND Peter NORTH Kathryn BIRNEY Ewan |
|---|---|
| Rok publikování | 2021 |
| Druh | Článek v odborném periodiku |
| Časopis / Zdroj | Cell Genomics |
| Fakulta / Pracoviště MU | |
| Citace | |
| www | https://www.sciencedirect.com/science/article/pii/S2666979X21000367 |
| Doi | http://dx.doi.org/10.1016/j.xgen.2021.100029 |
| Klíčová slova | CLINICAL LABORATORIES;MATCHMAKER EXCHANGE;PRECISION MEDICINE;CANCER;BIOBANK;DISCOVERY;CLASSIFICATION;MUTATIONS;SCIENCE;CLINVAR |
| Popis | The Global Alliance for Genomics and Health (GA4GH) aims to accelerate biomedical advances by enabling the responsible sharing of clinical and genomic data through both harmonized data aggregation and federated approaches. The decreasing cost of genomic sequencing (along with other genome-widemolecular assays) and increasing evidence of its clinical utility will soon drive the generation of sequence data from tens of millions of humans, with increasing levels of diversity. In this perspective, we present the GA4GH strategies for addressing the major challenges of this data revolution. We describe the GA4GH organization, which is fueled by the development efforts of eight Work Streams and informed by the needs of 24 Driver Projects and other key stakeholders. We present the GA4GH suite of secure, interoperable technical standards and policy frameworks and review the current status of standards, their relevance to key domains of research and clinical care, and future plans of GA4GH. Broad international participation in building, adopting, and deploying GA4GH standards and frameworks will catalyze an unprecedented effort in data sharing that will be critical to advancing genomic medicine and ensuring that all populations can access its benefits. |
| Související projekty: |