Molecular dynamics simulations of RNA kissing loop motifs reveal structural dynamics and formation of cation-binding pockets
Autoři | |
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Rok publikování | 2003 |
Druh | Článek v odborném periodiku |
Časopis / Zdroj | Nucleic Acids Research |
Fakulta / Pracoviště MU | |
Citace | |
Obor | Biofyzika |
Klíčová slova | RNA; kissing loop motifs; molecular dynamics; cation-binding pockets |
Popis | Loop-loop interactions between RNA hairpins represent an important class of RNA-RNA recognition motifs. These `kissing-loop' complexes participate in antisense regulation of a variety of cellular processes in prokaryotic cells and in bacteriophages. To under-stand the function of kissing complexes, we have carried out molecular dynamics simulations on two types of RNA kissing structures. |
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