BOX COUNTING METHOD IN RECORD, PROCESSING AND EVALUATION OF GENOMIC SIGNALS
| Autoři | |
|---|---|
| Rok publikování | 2010 |
| Druh | Článek ve sborníku |
| Konference | X. pracovní setkání fyzikálních chemiků a elektrochemiků - sborník příspěvků |
| Fakulta / Pracoviště MU | |
| Citace | |
| Obor | Analytická chemie, separace |
| Klíčová slova | Fractals; dimension; Citrobacter youngae; Homo sapiens |
| Popis | Fractals are geometrical shapes with noninteger dimension and invariation against change of scale factor. For each geometrical shape, one parameter, dimension, can be calculated. For calculation, Box Counting Method (BCM) was chosen. Determination of dimension on one level of resolution is not sufficient, it is necessary to subsequently process it and determine multifractal coefficient. Aim of interest consists in image analysis obtained from linear sequence of DNA code. For analysis itself, sequences of Homo sapiens Atlase and Citrobacter youngae were chosen. Results of calculation are fractal coefficients derived from dimensions of generated structures. This result enables to introduce criterion for sequences determination. Graphical outputs may be also represented as multidimensional alternative transformation of linearly recorded genomic signal. Algorithms are developed in environment of matrix laboratory MATLAB. Origin of data is in public database EMBL (ESI) and GenBank (NCBI). |
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