Human native endocarditis caused by Streptococcus canis-a case report

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Authors

MALIŠOVÁ Barbora ŠANTAVÝ Petr LOVEČKOVÁ Yvona HLADKÝ Bořivoj KOTÁSKOVÁ Iva POL Jiří LONSKÝ Vladimír NĚMEC Petr FREIBERGER Tomáš

Year of publication 2019
Type Article in Periodical
Magazine / Source Journal of Pathology, Microbiology and Immunology, APMIS
MU Faculty or unit

Faculty of Medicine

Citation
web http://dx.doi.org/10.1111/apm.12905
Doi http://dx.doi.org/10.1111/apm.12905
Keywords Streptococcus canis; infective endocarditis; PCR; sequencing
Description We report a very rare case of Streptococcus canis native infective endocarditis in a 73-year-old woman living in close con- tact with her dog. Her echocardiography showed large calcifications in the mitral annulus, massive regurgitation below the posterior leaflet, and adjacent vegetation. Blood culture was positive for Streptococcus Lancefield group G. A coronary artery bypass and mitral valve replacement had to be done. Streptococcus canis was detected in a heart valve using a broad range PCR followed by 16S rRNA and confirmed by tuf gene sequencing, while tissue culture remained negative. The patient was not bitten by her dog nor did she have comorbidities or skin ulcers. She fully recovered.
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