Human native endocarditis caused by Streptococcus canis-a case report

• Autoři: MALIŠOVÁ Barbora; ŠANTAVÝ Petr; LOVEČKOVÁ Yvona; HLADKÝ Bořivoj; KOTÁSKOVÁ Iva; POL Jiří; LONSKÝ Vladimír; NĚMEC Petr; FREIBERGER Tomáš
• Rok publikování: 2019
• Druh: Článek v odborném periodiku
• Časopis / Zdroj: Journal of Pathology, Microbiology and Immunology, APMIS
• Fakulta / Pracoviště MU: Lékařská fakulta
• www: http://dx.doi.org/10.1111/apm.12905
• Doi: http://dx.doi.org/10.1111/apm.12905
• Klíčová slova: Streptococcus canis; infective endocarditis; PCR; sequencing
• Popis: We report a very rare case of Streptococcus canis native infective endocarditis in a 73-year-old woman living in close con- tact with her dog. Her echocardiography showed large calcifications in the mitral annulus, massive regurgitation below the posterior leaflet, and adjacent vegetation. Blood culture was positive for Streptococcus Lancefield group G. A coronary artery bypass and mitral valve replacement had to be done. Streptococcus canis was detected in a heart valve using a broad range PCR followed by 16S rRNA and confirmed by tuf gene sequencing, while tissue culture remained negative. The patient was not bitten by her dog nor did she have comorbidities or skin ulcers. She fully recovered.

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