The Reactivity Study on N3,N3-(3-Oxapentan-1,5-diyl)-N1-(2-phenyl-3,4-dihydroquinazolin-4-yliden)thiourea

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Authors	MOHAMED Walid Fathalla ČAJAN Michal MAREK Jaromír PAZDERA Pavel
Year of publication	2001
Type	Article in Proceedings
Conference	Proceedings of ECSOC-5, The Fifth International Electronic Conference on Synthetic Organic Chemistry, http://www.mdpi.org/ecsoc-5.htm
MU Faculty or unit	Faculty of Science
Citation
Web	http://www.mdpi.org/ecsoc-5.htm
Field	Organic chemistry
Keywords	Quinazolines; thioureas; domino-reactions; N3;N3-(3-oxapentan-1;5-diyl)-N1-(2-phenyl-3;4-dihydroquinazolin-4-ylidene)thiourea;
Description	The thioamide represented by the model compound N3,N3-(3-oxapentan-1,5-diyl)-N1-(2-phenyl-3,4-dihydro-quinazolin-4-ylidene)thiourea contain both multi-functional nucleophilic and electrophilic characters. It reacts regioselectivity with amines, amines in the presence of H2O2 and alkyl halides to give the transamination reaction products, the oxidative desulfurization products and the S-alkyl product, respectively. FTIR, 1H NMR, 13C NMR, mass spectroscopy and X-ray identified compounds.
Related projects:	Chalcogen organic compounds - synthesis, transformation and structure elucidation Structure and character of bonding, properties and analysis of synthetic and natural molecular ensembles