Detection of Treponema pallidum subsp. pallidum SS14 from Skin Lesions,Serum, and CSF in an Infant with Congenital Syphilis after Clindamycin treatment of the mother during pragnancy.

• Title in English: Detection of Treponema pallidum subsp. pallidum SS14 from Skin Lesions,Serum, and CSF in an Infant with Congenital Syphilis after Clindamycin.
• Authors: WOZNICOVÁ Vladana; ŠMAJS David; WECHSLER Dan; FLASAROVÁ Magdalena; MATĚJKOVÁ Petra
• Year of publication: 2007
• Type: Article in Periodical
• Magazine / Source: Journal of Clinical Microbiology
• MU Faculty or unit: Faculty of Medicine
• Field: Microbiology, virology
• Keywords: congenital syphilis; T. p. pallidum SS14; DNA sequencing; treatment of syphilis; clindamycin
• Description: We report a case of early congenital syphilis in a newborn after inadequate clindamycin treatment in pregnancy. Using PCR detection of tmpC (TP0319) and DNA sequencing of genes TP0136 and TP0548, DNA sequences identical to Treponema pallidum subsp. pallidum strain SS14 were detected in the infant-s skin lesions, serum, and cerebrospinal fluid.

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