Spectroscopic and Theoretical Insights into Sequence Effects of Aminofluorene-Induced Conformational Heterogeneity and Nucleotide Excision Repair

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Authors	MENENI Srinivasa SHELL Steven GAO Lan JURECKA Petr LEE Wang SPONER Jiri ZOU Yue CHIARELLI Paul CHO Bongsup
Year of publication	2007
Type	Article in Periodical
Magazine / Source	Biochemistry
MU Faculty or unit	Faculty of Science
Citation
Field	Physical chemistry and theoretical chemistry
Keywords	nucleotide; HPLC; NMR; CD; MD simulations; QM calculations
Description	A systematic spectroscopic and computational study was conducted in order to probe the influence of base sequences on stacked (S) versus B-type (B) conformational heterogeneity induced by the major dG adduct derived from the model carcinogen 7-fluoro-2-aminofluorene (FAF).
Related projects:	Proteins in metabolism and interaction of organisms with the environment Biomolecular centre