Informace o projektu
Czech Infrastructure for Integrative Structural Biology
(CIISB)
- Kód projektu
- LM2015043
- Období řešení
- 1/2016 - 12/2019
- Investor / Programový rámec / typ projektu
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Ministerstvo školství, mládeže a tělovýchovy ČR
- Velké infrastruktury pro výzkum, vývoj a inovace
- Fakulta / Pracoviště MU
-
Středoevropský technologický institut
- prof. RNDr. Vladimír Sklenář, DrSc.
The Czech Infrastructure for Integrative Structural Biology (CIISB) is a distributed infrastructure of the core facilities and central laboratories of CEITEC (Central European Institute of Technology, Brno) and BIOCEV (Biotechnology and Biomedicine Centre, Vestec, Prague-West) providing expertise and access to technologies used for integrative approaches to structural analysis of biologically important cellular components and macromolecules - proteins, nucleic acids, and their complexes. CIISB, equipped with the cutting-edge technologies (total investments will exceed 750 mil. CZK by the end of 2015), will offer access to the equipment and expertise in the following fields: high-field NMR spectroscopy; high throughput crystallization of biological macromolecules; X-ray diffraction techniques; Bio-SAXS measurements; AFM imaging; characterization of proteins, nucleic acids and complexes by biophysical methods including microcalorimetry, dynamic light scattering, and surface plasmon resonance; high-end cryo-electron microscopy and tomography allowing studies of cellular structures, organelles, and biomacromolecular complexes by 3D imaging; protein expression in eukaryotic cells; high-end mass spectrometry characterization of biomacromolecules; determination of protein post-translational modifications; MS-based peptide mapping/sequencing; high throughput sequencing and proteomic services. CIISB infrastructure aims to provide a high quality open access services in provision of methods and techniques on a level of national and trans-national importance. CIISB as National Affiliated Center is a part of the ESFRI projects INSTRUCT.
Publikace
Počet publikací: 252
2018
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Chiral Bambusurils for Enantioselective Recognition of Carboxylate Anion Guests
Chemistry - A European Journal, rok: 2018, ročník: 24, vydání: 58, DOI
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Identification and partial characterization of a novel serpin from Eudiplozoon nipponicum (Monogenea, Polyopisthocotylea)
Parasite, rok: 2018, ročník: 25, vydání: DEC, DOI
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Inhibice P-glykoproteinu dibenzocyklooktadienovými lignany z rostliny Schizandra chinensis
Rok: 2018, druh: Konferenční abstrakty
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Interplay of Through-Bond Hyperfine and Substituent Effects on the NMR Chemical Shifts in Ru(III) Complexes
Inorganic Chemistry, rok: 2018, ročník: 57, vydání: 15, DOI
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Introduction to fluorescent protein microarrays
Rok: 2018, druh: Popularizační texty
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Irradiation by gamma-rays reduces the level of H3S10 phosphorylation and weakens the G2 phase-dependent interaction between H3S10 phosphorylation and gamma H2AX
Biochimie, rok: 2018, ročník: 154, vydání: NOV, DOI
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Limitations of routine MALDI-TOF mass spectrometric identification of Acinetobacter species and remedial actions
Journal of Microbiological Methods, rok: 2018, ročník: 154, vydání: NOV 2018, DOI
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Looking for inhibitor: structural and functional analysis of novel bangle lectin PHL from Photorhabdus asymbiotica
Rok: 2018, druh: Konferenční abstrakty
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MALDI-MS practical training for highschool students
Rok: 2018, druh: Popularizační texty
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MALDI-MS profiling course I
Rok: 2018, druh: Popularizační texty