Project information
Plasticity of Regulatory Mechanisms of the Central Nervous Systems
- Project Identification
- MSM141100001
- Project Period
- 1/1999 - 1/2004
- Investor / Pogramme / Project type
-
Ministry of Education, Youth and Sports of the CR
- Research Intents
- MU Faculty or unit
- Faculty of Medicine
- Keywords
- Plasticity; Regulatory Mechanisms; Central Nervous System; Preclinical and Clinical Aspects; Neurobiology; Neurophysiology; Neuroanatomy; Neuropharmacology; Clinical Neurology; Psychiatry; Regeneration Processes; Neurotransmitters; Epilepsy
The central nervous system, its neurobiological mechanisms and the possibilities of influencing them externally have become the subject of the BRAIN DECADE in the research strategy announced by president Bush and enacted in the USA in 1990, to which Europe joined in 1992. The intentions included into the project being submitted, i.e. the investigation of the neurobiological and neurophysiological mechanisms of the control of the motor and mental functions, of their abnormalities, and the possible therapeutic or preventive influencing of these are completely in line with the "Brain Decade" programme. The project a based on an integration of the of pre-clinical aspects of the research in neuroanatomy, neurophysiology, pharmacology, and clinical research in the clinical fields of neurology, neurosurgery, plastic surgery and psychiatry. 16 postgraduate students have been included into this faculty research.
Publications
Total number of publications: 704
2004
-
Stimulace nervus vagus v terapii farmakorezistentní epilepsie.
Neurologie pro praxi., year: 2004, volume: 2, edition: 2
-
The impact of the cannabinoid CB2 receptor agonist JWH 015 on development of methamphetamine sensitization to locomotor/exploratory activity in mice
Psychiatrie, year: 2004, volume: 8, edition: Suppl. 1
-
The impact of the cannabinoid CB2 receptor agonist JWH 015 on development of methamphetamine sensitization to locomotor/exploratory activity in mice
Homeostasis in Health and Diseases, year: 2004, volume: 43, edition: 1
-
The influence of cannabinoid CB2 receptor agonist JWH 015 on sensitization to methamphetamine in the model of mouse agonistic behaviour
Psychiatrie, year: 2004, volume: 8, edition: Suppl. 1
-
The influence of cannabinoid CB2 receptor agonist JWH 015 on sensitization to methamphetamine in the model of mouse agonistic behaviour
Homeostasis in Health and Diseases, year: 2004, volume: 43, edition: 1
-
The influence of felbamate on sensitization to methamphetamine behavioural effects in mice.
European Neuropsychopharmacology, year: 2004, volume: 14, edition: Suppl. 3
-
The influence of selective agonists at cannabinoid CB1 receptor and CB2 receptor on sensitization to methamphetamine behavioural effects in mice.
European Neuropsychpharmacology, year: 2004, volume: 14, edition: Suppl. 1
-
The monitoring of QTc interval in patients treated psychotropic drugs
European Neuropsychopharmacology, year: 2004, volume: 14, edition: suppl. 3
-
The opioid antagonist naltrexone reduces the reinforcing effects of Delta(9)-tetrahydrocannabinol (THC) in squirrel monkeys
Psychopharmacology, year: 2004, volume: 173, edition: 1-2
-
The pitfalls of antidepressant treatment (gender differences)
Psychiatrie, year: 2004, volume: 8, edition: suppl.4