Informace o projektu
Czech Infrastructure for Integrative Structural Biology
(CIISB)
- Kód projektu
- LM2015043
- Období řešení
- 1/2016 - 12/2019
- Investor / Programový rámec / typ projektu
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Ministerstvo školství, mládeže a tělovýchovy ČR
- Velké infrastruktury pro výzkum, vývoj a inovace
- Fakulta / Pracoviště MU
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Středoevropský technologický institut
- prof. RNDr. Vladimír Sklenář, DrSc.
The Czech Infrastructure for Integrative Structural Biology (CIISB) is a distributed infrastructure of the core facilities and central laboratories of CEITEC (Central European Institute of Technology, Brno) and BIOCEV (Biotechnology and Biomedicine Centre, Vestec, Prague-West) providing expertise and access to technologies used for integrative approaches to structural analysis of biologically important cellular components and macromolecules - proteins, nucleic acids, and their complexes. CIISB, equipped with the cutting-edge technologies (total investments will exceed 750 mil. CZK by the end of 2015), will offer access to the equipment and expertise in the following fields: high-field NMR spectroscopy; high throughput crystallization of biological macromolecules; X-ray diffraction techniques; Bio-SAXS measurements; AFM imaging; characterization of proteins, nucleic acids and complexes by biophysical methods including microcalorimetry, dynamic light scattering, and surface plasmon resonance; high-end cryo-electron microscopy and tomography allowing studies of cellular structures, organelles, and biomacromolecular complexes by 3D imaging; protein expression in eukaryotic cells; high-end mass spectrometry characterization of biomacromolecules; determination of protein post-translational modifications; MS-based peptide mapping/sequencing; high throughput sequencing and proteomic services. CIISB infrastructure aims to provide a high quality open access services in provision of methods and techniques on a level of national and trans-national importance. CIISB as National Affiliated Center is a part of the ESFRI projects INSTRUCT.
Publikace
Počet publikací: 272
2017
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Hybrid microporous and mesoporous organosilicate covalent polymers with high porosity
MICROPOROUS AND MESOPOROUS MATERIALS, rok: 2017, ročník: 240, vydání: March, DOI
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Characterization of lectin AFL from opportunistic pathogen Aspergillus fumigatus – combining a broad spectrum of biophysical methods
Rok: 2017, druh: Konferenční abstrakty
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Characterization of novel bangle lectin from Photorhabdus asymbiotica with dual sugar-binding specificity and its effect on host immunity
PLoS Pathogens, rok: 2017, ročník: 13, vydání: 8, DOI
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Luminescent Ruthenium(II) Polypyridyl Complexes as Nonviral Carriers for DNA Delivery
Chemistry - An Asian Journal, rok: 2017, ročník: 12, vydání: 2, DOI
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MALDI-MS profiling course
Rok: 2017, druh: Uspořádání workshopu
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MALDI-MS profiling course - November 2017
Rok: 2017, druh: Uspořádání workshopu
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MALDI-MS profiling course - October 2017
Rok: 2017, druh: Uspořádání workshopu
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MAMP (microbe-associated molecular pattern)-induced changes in plasma membrane-associated proteins
Journal of Plant Physiology, rok: 2017, ročník: 210, vydání: March, DOI
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Metal alloy nanoparticles: synthesis, characterization, and size-dependent phase diagram calculations
Rok: 2017, druh: Konferenční abstrakty
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Modulation of Bambusuril Anion Affinity in Water
Chemistry - A European Journal, rok: 2017, ročník: 23, vydání: 37, DOI